Adult & adolescents >14 yr Initially 15-45 mL daily. Maintenance dose: 15-30 mL daily. Childn 7-14 yr Initially 15 mL daily. Maintenance dose: 15 mL daily.
Galactose or fructose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption. Lactose intolerant patients. Patients w/ DM. Reduced dose or discontinue treatment if symptoms like meteorism or bloating occur in patients w/ gastro-cardiac syndrome (Roemheld syndrome) after intake. Can lead to diarrhea & electrolyte imbalance in chronic use. Drink sufficient amounts of fluids during therapy. Infants & small childn w/ autosomal recessive hereditary fructose intolerance. Elderly.
Flatulence, abdominal pain. Nausea & vomiting; diarrhea (high dose; sometimes including electrolyte imbalance).
Drug Interactions
May increase K loss w/ thiazides, steroids & amphotericin B. Can increase effect of cardiac glycosides. Decreased pH value in the colon can inactivate 5-ASA.